Karen... Are you familiar with Dr. Daniel Amen's work? He is a clinical neuoscientist and psychiatrist who uses SPECT imaging to determine the areas of the brain responsible for depression, anxiety, OCD, etc.He believes that problems in the limbic system are responsible for bonding disorders, mood disorders,negative thinking, guilt, decreased interest in sex, etc. He goes through some non-medical strategies to enhance positive thought patterns and connections, and has some medication advice as well...one of them is St Johns Wort, containing 0.3% hypericin at 500mg 2x a day.