Antidepressants take about a month to kick in, but they're not "happy pills". Eat chocolates in the meantime. I'm serious.
Anyway, insofar as experiences with ADs, there was a time when the wife used to get real crotchety with PMS. Sleepless nights, every little thing was a problem, severe mood changes, you name it, man, it was driving me nuts. So the doctor prescribed Wellbutrin, and after a few weeks of my taking it, her antics didn't bother me anymore.