General opinion on this bb is that ignoring/being dark will make the other person angry. I wouldn't reply to her email too quickly tho.
Then send a short note, 'Been a little busy lately, no infections (or whatever the story is on the knee) sorry to hear about the girls, I know you are taking good care of them.'
Then let her contact again. (but then that's my opinion, let's see what every1 else has to say!) T