I think you are "owning her problems" too much. She realizes something is not right with her mood and has tried various AD's...that is her way of trying. Now she wants to see how she feels without the help of the medication...she is recognizing there is no easy cure for feeling good. She is trying.
On your date nite, you stayed connected to her by talking and staying strong and keeping things lite. It worked, and that's " all" you need to do...be there for her. She responded. Hopefully she will begin to see that the best medicine is a healthy, open connection with you.
So don't get weighed down, or in PM-speak, "fused" with her emotional state.