'Maybe it's over with her'
THIS MEANS IT'S NOT, OK? If it was, he would be telling you in no uncertain terms that it is over.
More crumbs than Hansel and Gretel there.
And yes, the depression sounds spookily similar to my H. We can't fix them, they have to grow up and take responsibility for their lives. And we need to do the same. Keep on GALing.