The request to move out will undoubtedly bring terror to the situation. You will get blamed for all of her ills and you will be the "reason" she's moving out. My W was having a full blown affair, coming home at all hours of the night. After several weeks I decided to move out. Guess who got the blame for breaking up a family?
In addition to blame, be ready for that tiny violin regarding children, finances, etc...
They do not like dealing with the consequences of their decisions.