SM34: YES! This happened to me and my spouse too! He went on Wellbutrin for stress at work, mild depression and within months, turned into another person. Suddenly wanted a divorce, had an online emotional affair with one woman and then started dating a coworker. He moved out and is now having a full blown affair. Last we spoke he said he'd gotten off the medication but I don't even know whether I should believe him.

Problem is, he was already in the thick of it with this other woman. Too far along to turn back even if he had gotten off the drugs. Hard to compete with the intense sexual feelings of a new attraction.

The symptoms of emotional blunting from antidepressants overlap with classic midlife crisis symptoms, but I really think the drugs put him in a frame of mind of suddenly completely losing all attachment to me, becoming cold/cruel, and thinking it was OK to have affairs.

Tomorrow I'm going on antidepressants myself. I'm not a fan but I'm in such a dark place, I need to. Kind of hoping I'll lose all my feelings for him. Would be easier...