Thyroid disorder. Lack of thyroxine causes serious metabolic issues and is unlikely to cause personality disorder. Behavioural issues deriving from metabolic imbalances, confusion, severe tiredness and being weary.
Abuse?
Unlikely.
I have no thyroid function following radiotherapy in 2001, and am part of a large support group and usually thyroid removal has a damping effect on bad behaviour rather than enhancing. People with disorders can have thyroid issues too. Sort of like having a broken leg and Malaria.
Can't comment on the brain tumour, as I have no experience.
My 2c
V
Freedom is just another word for nothing left to loose. V 64, WAW