First, no anti depressants. Both of us have been free of drug issues, prescription or otherwise.
Second, the single biggest issue is the loss of emotional connection. My W's primary love language is quantity time and conversation and over 20 years and 5 kids she feels we drifted apart and that it's no one's fault. When she is angry, she says I prioritized myself and the kids over her. When we lost the emotional connection, she started to resent the childcare and housekeeping and sex--these changed from things she enjoyed to duties she resented...she felt used. She started questioning everythkng and blaming religion, society, her family and me for her situation. She attempted to talk to me about some of these things, but I didn't listen. As you suspected, she made new divorced and single friends who have been her cheerleaders in her new endeavors.
Gordie 40s W 40s M20+ kids 2016 BD W fantasy affair w OM1 I do everything wrong 2017 I start to DB W says TLTL files for D PA w OM2 2018 I do LRT W drops filing and OM2 situation slowly improving