Lee,
I would be very concerned over this. In fact, I think you should make the appt. If she is depressed, it is doubtful that she can muster the will to even make the appt herself.

The reason I say this is not because she is damaging your marriage--which she obviously is. But rather, she just missed out on 24+ hours of her daughters life!! As a mother, I can't imagine the horror and shame that she will feel when she finally snaps out of this fog and realizes how much she missed while sleeping.
Help her avoid this, for her sake and your D's. Make the appt and perhaps she can start being treated for whatever is ailing her. I think that any therapist who heard how much sleep she got in one weekend would immediately look into testing to see what is going on.

Hope you find some answers quickly!

Honey