The chances of him taking any kind of depression meds or even talking to a professional about it would be less than zero. Trying to discuss it with him, I feel, would make him angry and drive a further wedge between us.
So I guess not discussing it is the best course of action.
People that are depressed are normally in denial.
He needs to decide on his own that he wants to FIX himself, you telling him is not going to help that.