"In many of our cases (especially husbands leaving) spouses had serious health issues or had to deal with recent death in the family. Why does that make them Want to leave instead of recognize the fact that life is short, let me me work with and appreciate the things that are truly important. (Especially since it's not just spouse that are being left but kids as well). What is going on psychologically?"
I am not a psychologist but I'll take a stab at it. I guess that the triggering event coalesces with some MLC issues. The individual is unhappy with they're circumstance and they feel this may be they're last chance to make they're life match they're delusion.
That's my guess but you know what free advice is worth, be well