It is indeed his life in crisis. He is 35, but we married young, so we have been married for 12 years this year. We didn't start having kids until a few years ago, but I think he might feel missed out of things he could have done when he was younger/single. My IC also told me OW is just a by-product of his crisis, that might be true. He was low and she was there.
I think I will suggest that I could help him a little with a condition of him trying to save money prior to the trip as well(less outing etc) and that this is going to be his solo trip without OW involved. He should also ask for his parents to watch the kids during the day. (That's what we did for his last trip)
It is frustrating and painful to see the loved one suffering, and you can not do much...