Wow...you know I had a Mother that was addicted to alcohol for most of my life and a younger brother that was addicted to drugs and alchol. Have you joined any support groups for families of addicts? I highly suggest you do if you haven't. Otherwise you tend to fall into the co-dependent tendencies. If your wife is still using then you are talking to the addiction. It sounds like you are so used to the merry go round that you have lost sight of what healthy is.
My advice would be join a support group for families of addicts. Read DR and DB. GAL and a PMA. You will be ok no matter what happens. We only get one life. Live yours. Your wife sounds like she needs lots of help. Help that is beyond you. Give her the space to get that help. She won't be motivated to do that if you continue to rescue her and prevent her from suffering from the consequences of her own behavior.
She couldn't control what happened in her life when she was young. She can now get help and move towards a healthier happier life. I stepped back from my own Mother when she was drinking and I had kids of my own. She did sober up for ten years before she passed. My brother I don't have a relationship with. His addictions won. I don't harbor any anger and hope he's safe. I'm close to my other two brothers.
The serenity prayer always helps me. If you don't believe in God replace with higher power or whatever your belief is.
God grant me the serenity to accept the things I cannot change. Courage to change the things I can and the WISDOM to know the difference
Me 52 H 44 T9 M 5 BD 12/11 H split 8/12 OW moved in 12/12 OW gone for good 6/14 We get closer again 9/14 SD 13 Me 4 Grown
Accept what is...let go of what was and have faith in what will be.