I wanted to circle back to explain why I think it is important for Vertex to respond to W's email.

1) It is courteous and respectful to acknowledge her heartfelt message
2) W's wall has come down a bit to reach out to Vertex
3) One needs to take this situation on context: mutual RO which has prevented them from communicating. Zero communication means zero connection.

Vertex, send out the simple response and then let it go. Don't try to reach out again or prolong it. You have been doing really well respecting W's space and her desire for no contact.

Keep your expectations at zero or at least low.