Only God Himself can change hearts, brother, and even then there's that whole "free will" thing. Pesky, that. My sister likes to say "God will break you, but first you have to WANT to be broken." Very true.
The hardest thing I think I had to do is my entire sitch 7 years ago was let go of my wife, and give her to God. To fully realize -- intellectually, emotionally and spiritually -- that I could not control her nor the outcome. I will never forget the moment -- I was in the backyard, mowing my lawn of all things, sweating my azz off in the 90+ degree Florida heat and humidity, and I just started bawling like a baby. I mean I take my role as husband and father seriously, and I did do the basic things (legal, financial, prayer etc.) and lay down certain core boundaries to protect my family but ultimately I had to just --spiritually -- "lay my wayward wife at the foot of the Cross" and give her to our Lord to deal with. I told Him, honestly, that I had done what I can, and for Him to please protect her because I can't seem to get through to her.
I believe those prayers were answered, and I pray that they will be for you, too.