Go check out a couple of websites dealing with bipolar disorder (manic despressive syndrome).
A good place to start is http://bipolar.about.com Check out the essentials bar at the left. If the symptoms match your wife, the last thing she needs is prozac. I am not saying that she is bipolar, but some of the things you mentioned about her could indicate that there are some chemical issues at work.
Disclaimer: My advice is worth exactly what you are paying for it :-)
-NOPkins-
I will ferret out an affair at any opportunity.
-An affair is the embodiment of entitlement, fueled by resentment and lack of respect. -An infidel will remain unreachable so long as their sense of entitlement exceeds their ability to reason.