I think it's certainly possible your W is experiencing something similar to a MLC. My W is 35 and I believe that is partly what is happening with her as well, although my W's may also be partly due to clinical depression that possibly started out as post partum.
Perhaps you could suggest to your W that being M does not necessarily have to mean a loss of freedom. She may just need more time to do things on her own, find interests for herself etc.
Me-40,W-37 D7, D5, S3 Separated Oct 3/2013 T 11 YRS M 7 YRS