I think it's good to be honest. Don't make her feel guilty or act negatively about the kids not asking about her. You could even say, of course they miss you. They were asking me "this" and "this." She's got a lot of guilt to deal with and it's hard for them to deal with situations like this in a normal way. You and I may feel guilty and it would cause us to make positive changes and spend more time with the kids. Your W may feel guilty and this would cause her to think that everyone should hate her, she cant fix anything, and everyone is better off without her.
M38,H39 M:16Y BD:8/12 OWDB:11/12 S:11/12-5/13 "Temp" home:6/13 OW dropped:9/13 "I love you":12/13 H ring on:2/14 Depression back:5/15 "I'm done:" 7/15 H moved out: 3/16 H moved back: 12/16 Working on us: 3/17