Grizz, this is tough to hear. I agree with AS that it is not over. Continue to DB.
When my W spoke of separating, she had some unrealistic fantasy that she could live next door, we would be best friends, and she could come and go visiting our 3 girls as she pleased. Maybe when your wife sees the reality of her being alone, it will cause her to reevaluate her decisions and the source of her unhappiness.
Whatever, continue DB, it's for you as well as your M.