Any thoughts on his wanting to move out for space, now to deal with his detachment from her too, among all the other stuff he is dealing with?
He feels trapped in a cage. If he says he wants to move out, then tell him you understand why he feels that way and you support his decision. Don't specifically tell him to move out, just validate his emotions and support whatever he decides. There's a chapter in Love Must Be Tough that talks about this, if the LBS throws the cage door open then suddenly the WAS isn't sure they really want to leave. They originally wanted to leave because they felt trapped, but once the door is open that trapped feeling goes away. They also start questioning why their spouse is suddenly letting them go- is she ready to move on? Am I losing her? What now? By going along with them you're changing the dynamic and making them question their plan. And he may very well leave, but you have to realize you can't control whether he leaves or stays so it's best not to try because if you try then you're just applying pressure to him and driving him away.