I don't think I have a option now other than to be supportive when I can, always nice and calm, and try to protect my kids and myself legally.
This is always a good stance.
I tried to bring it up delicately. We've talked a bit... I told her she seemed to change when she went from taking anti-depressants to another class of meds (its for joint paints but depression and mood swings are on the symptom list). I tried to dance around it. She has prescripted meds from a physc nurse practitioner relative (which I think is inappropriate). That person will not answer my calls (called twice)... and sent them text saying I was concerned for wife and wanted to discuss it with them... they called wife instead and she was pissed. That is the extent of it. She went from just " I don't love you and want to separate" to a lot of anger, hate, and now paranoia.
Also there is the possibly that wife is getting off anti-depressants because she knows it will be a custody issue... and getting off them is causing her to go downhill mentally.