Your W does sound depressed. Depression is present through out the crisis.
Has she been to see a doctor? ADs will NOT end her crisis. They may, however, help her to cope and function in everyday life. She could probably do with a hormone eval. as well.
Her appearance sounds about right for a MLCer. The stress, depression and guilt take their toll and tend to age them.
Be glad of your W isolation. My H lives with the ow. I'd much rather he lived by himself if it's not with me. It is normal for them to isolate themselves. It's an external sign for an internal struggle.
Do yourself a huge favor. Stop trying to determine what her actions mean. You really have no clue and basically because the MLCer doesn't either. Detach and love her from a distance. Do not pressure her. You'll just lengthen her crisis.
If OM is still present even though he is in China, your wife is still in Replay.
She has to go through this by herself. You survive your own journey by getting out there and GALing and being the best possible Radio that you can be. Be that man who attracted her in the first place.
When your son questions things tell him his mom is going through some things that she has to work out. It's going to take a while and in the mean time I am here for whatever you need.
Time and patience Radio. Time is something the LBS has a lot of. Patience is what the LBS needs a lot of to survive the MLCer's crisis.