First, you have to determine if there's anyone else involved. That changes your strategy. Next, you need to stay on the wagon. That's a huge, important change that'll do more for you, your son, and your relationship than anything else.
Next, you need to really understand why she's unhappy. Lack of attention, hostile home environment, what. Then do 180s; take on small thing at a time and do the opposite. Don't expect her to notice, it's not for her. It's for you. Keep doing these things until they become firm habits
Next, try to take care of yourself and your health. Try to find some activities that are individual that make you feel good about yourself, that you've always liked. Be sure to get lots of rest, and eat well. Weight loss is very common when you start this Devastation Diet. Between the stress, my exercising, and changing my diet, I've lost over 40 lbs, and I'm in the best shape since I was in my 20s.
Finally, spend time with your son. These years are priceless, and not only will he appreciate the attention, your wife will notice. Women like fathers who are active in their kid's lives. And seeing you be a loving, nurtering father really brings out strong feelings, feelings your wife can't ignore.