I think you should read SunnyD's thread... Her H wants to move out and there's no indication that he's cheating on her at all.. He's miserable and doenst' want to work on the marriage at all...
She's trying to turn him around...
But yes it is possible to have a wayward who wants out who is NOT having an affair... People do leave marriages for other reasons besides having an apparently viable alternative
From what I have read conflicts over finances is the most common reason for divorce, not infidelity