wii,
No side effects from SAM-e.
With natural amino acid supplements, I got off ADs a quite a while ago.
Check out The UltraMind Solution by Mark Hyman. At the very least, go to a bookstore and take the short quizzes in the beginning of the book. They showed me (later confirmed by blood tests) what amino acids I was deficient in.

People do not suffer depression because their brains are deficient in Zoloft, Lexapro, et al. Often, they are deficient in neurotransmitter-supporting amino acids.

wii, last night on my thread you mentioned quitting alcohol 30 years ago. How old are you, if I may ask?

Gardener

"My soul, be satisfied with flowers,
With fruit, with weeds even; but gather them
In the one garden you may call your own."
Cyrano deBergerac