Gardener, I've read about Sam-E. There's a couple of other alternatives out there too. Did you have or do you have any side effects from Sam-E? My Naturopath says SJW works well on the nervous system. I've always resisted using anything, natural or otherwise but I decided to try this and see if it gives me a little boost. I just don't like side effects of any type! I'm planning to do some Yoga regularly again as well. Before I got the Bronchitis I had just started again, then got sick. The liver detox I'm using contains Parsley,Beet, Dandelion and Uva-ursi leaf...it's sure cleaning me out!