wii,
For Liver support and health I use Milk Thistle (Nature's Way Thysilyn, specifically. Maybe three times a year I buy a bottle and use it up. It's not an everyday, all-the-time supplement.
Along with several Amino Acids, Sam-E has given me the same AD relief as ADs.
fwiw.

Gardener

"My soul, be satisfied with flowers,
With fruit, with weeds even; but gather them
In the one garden you may call your own."
Cyrano deBergerac