Oh, it can be saved, but she has to want to TRY. And SOMETHING (or someone) is blocking her from even wanting to try.
It makes me really angry when people don't even want to TRY to work on a marriage (unless of course there is abuse or something going on currently). 9 times out of 10, when these "symptoms" are presented, there's someone else in the picture, blocking them from wanting to try and messing with them physiologically.
