Yes, why not confront it? She will still probably deny it all but confront it. Tell you know where, what, when and who. DO NOT tell her how you know.
Do not be a jerk but be firm.
DO NOT fix things in her new place. Why would you do that? If she wants to leave, she should be a big girl. You fixing things in her new place is just enabling her.
You can never excommunicate her, you have kids together BUT you can go dark. Stop communicating about anything other than your kids.
DO NOT DO NOT DO NOT give her any money for her trip. Do NOT drive her to the airport. Do nothing to assist her with her adventure.
Me 44 She 46 S13 D9 M18 T23 3 years DB'ing Successfully busted