You are right. I don't think I will handle it well. How do I start to prepare myself for the possibility for her departure without giving the impression that I too want it to be over?? I will say I have done better recently reacting to her when she says she is leaving. I use to beg, then I would get upset and now I just ignore it even though it does get to me.
The best (only?) way I've seen it done around here is to adopt SmileyPerson's "Consider yourself already dead" (Band of Brothers) outlook. Maybe Coach's slightly-more-optimistic "Stockdale Paradox" but nothing more optimistic or hopeful than that.
In my experience, when you START from a basis of "he/she's cheating on me; this marriage is, for all intents and purposes, already dead," and then try to resuscitate it, you'll have more success.