Men should have sexual release, one way or the other, at least 20 times a month, for health reasons. Studies have shown that men who maintain this level of frequency have the lowest rates of prostate cancer.
By this measure, I'm in the lowest risk group as it relates to frequency of sex.
So, it could be said that it's harmful not to MB if you aren't having frequent sex. The frequency quoted as the "norm" for married couples is NOT sufficient to put you in the lowest risk group for prostate cancer.