What do you base this belief on? Have you checked it out?
Your wife sounds a LOT like my wife (went from living with her parents to living with me, SAHM, then got a job, suddenly not happy, etc., etc.), and there are a lot of "red flags" in your post. The good news is, it would help explain a lot, and would probably mean her "I don't love you" statements are just re-writing of marital history, which is reversible.