I'm sorry your going through all of this. I can't imagine going throught it and thinking it's behind you then having to deal with it all over again.
You have to make this about you and your children. Do what is best for you. When it comes to having a love one in crisis, no matter what you try, they have to resolve their issues before anything will change. It's sad but it's the way it is.
My wife is 29 and in full on crazy mode. Looking back it started very gradual 2 years ago after the birth of my son and then slowly came to a point where she checked out to la la land.
It's time to dig deep and be strong. Take care of yourself. You have to distance yourself and pretty much do your own thing. Work on you, take great care of your children (they need you now like never before) and as hard as it is at first get out and enjoy life, do something special for you. It gets better with time.