I am already living 90% of my life like I don't have a husband, because he isn't here! So I agree, other than getting over the hump of telling friends and family, and handling it with our kids (obv. the biggest challenge), not a whole lot else will be different than what I have gotten used to this past 18 months.
Except I think I will have more of a sense of freedom to make my own decisions....which is not a bad thing.