Hey Glam, as someone who has struggled her whole life with depression, I know how much he is hurting and how much it affects those that love him.
AD's sometime take months before you see any difference and he ABSOLUTELY should not go off them on his own - he will crash and the depression will deepen.
It took me years and many different meds before I finally found the ones that work. I know it is difficult to admit that he needs them. I never even too tylenol. I denied it too. But he has to keep trying.