It's tough, I just try to remind myself that everything fun that they seem to be doing is a quick fix to numb the pain they feel. I have to admit though, lately my wife's moods cycling back and forth so much has being trying my patience. I often struggle with having too much contact with her. I wonder if that slows things down.
I feel your pain about people thinking your nuts. They will never truly understand unless they go through it. Don't let it get you down. For our wive's to just suddenly change into the total opposite of what they were means to me that they must be going through some major stuff upstairs. All we can do is protect and work on ourselves and wait with the patience of a saint.
I know what you mean, at times I miss my wife something awful. Right now though I can't stand who she is and what she is chosing to do.