Guilt is a big issue b/c he has said many times he doesn't know how I could ever trust him/forgive him for what he has done. This is in large part b/c he does not forgive me, he harbors resentments toward me for things that he knows are not my fault. So if he can't forgive me for things that were not my fault, he doesn't believe I could truly forgive him for the things that are his fault.
He can't forgive himself. It sounds like he is running from himself and the guilt. Eventually he'll realize that he won't be able to outrun it.
I agree with Ali. This would be a good time to take a few steps back, and not make any sudden movements or decisions.