(Puppy likes that name, by the way) -- the trips are inappropriate, and that's just from the parts that your wife has chosen to disclose to you. If they make you uncomfortable, and you have told your wife that, then she should honor your wishes and find a more suitable way to get away with the girls (which is perfectly fine, btw).
If she won't, then she is putting her friendships ahead of her husband, which is wrong IMHO.