Well, I don't think he was "depressed" before. I think he was unhappy...but I think that is different from being depressed. In the past two years or so (while on the pills) I would say he was definitely in a state of depression.
Who knows, he may need them, but I don't think what he was taking was doing the trick. Judging from how he has been acting lately maybe they were doing more harm than good.
Or maybe there is no explanation for it and I am just over analyzing!