Thank you for the reponses. For me, I feel the AD ( in my case, effexor) initially caused a small weight loss, but after several months, I found I was putting on weight way too easily. I don't think there's been any major change in my eating/exercise habits to account for this; it just seems like my body is not running as efficiently. During the past few weeks I have been tapering off the AD, so I'll see what happens.