Sandi...you might try calling your doctor to see if there is anything you can take to help with the side effects until you get used to the medication...maybe eating something before taking the pill...or something as easy as that...I know my H had trouble at first but I can tell you at about the 14 day point they really kicked in on the depression part of it and he felt so much better emotionally that the residual effects were not so bad...and soon those pretty much diminished...