All depends on what type you are taking and how long you have been taking them for. I've taken them before but not for long. However my H has been on them for about a little over a year now and as much as I saw quick results, it did take some time for them to get into his system and have some consistent change in him. And there were quite a few ups and downs.
He is on Effexor and it works miracles (we both agree on that). He is taking 225mg (recently just reduced from 300) but the doctor doesn't really want him any lower than that for the time being. Also suggested he could supplement it with Wellbutrin. You also have to be careful if you are taking any other type of medication as it can interfere with it (and if you smoke pot it can reduce the effects of it too)
Heywyre
M - 57 H - 65 1st A-bomb - Nov 27/02 2nd A-bomb - Dec 13/06 together 21 years *************************** Insanity is doing something over and over and expecting different results (Albert Einstein)